Erythromelalgia, or Mitchell’s Disease is a rare disease seen in the lower extremities that cause neuropathic pain.
Erythromelalgia is a rare neurovascular peripheral pain disorder of blood vessels in the hands, feet, and face. Blood vessels are periodically blocked causing the skin of the hands, feet, and even face become hyperemic (red) and inflamed. This flushing causes burning pain. Triggers that cause these flares are heat, long periods of standing, activity, exertion, insomnia, and stress.
Research has found that there are two types of Erythromelalgia, primary and secondary. Secondary results from various other conditions such as essential thrombocytosis, mushroom or mercury poisoning, and some autoimmune disorders. Primary Erythromelalgia is linked to a genetic mutation of sodium channels on gene SCN9A.
Mitchell’s disease is very hard to diagnose, because most patient have flares when they are at home, making it difficult for a doctor to see the symptoms. The best way to diagnose the condition is by genetic testing.
For more on this rare disease that causes neuropathic pain, check out this website: www.erythromelalgia.org